Methylene Blue-The "Blue Molecule"
- Amy Anci, BS, MA

- Jun 16
- 3 min read
Updated: Jun 25

What Is Methylene Blue?
Methylene blue is a compound that’s been around since the 1800s. It started as a textile dye, but it’s also been used in medicine for over a century—mainly to treat certain blood disorders and infections. Lately, it’s getting attention for its potential benefits in supporting energy, brain health, and healthy aging.
Why Might Methylene Blue Matter for Menopausal Women?
As we move through menopause, changes in hormones can affect how we feel—especially our energy, mood, and memory. Methylene blue is being explored for its ability to:
Support energy levels: It may help our cells produce more energy, which can be helpful when fatigue sets in.
Protect brain health: Some research suggests it can help with memory, focus, and mental clarity.
Promote vitality: By supporting the body’s natural processes, it may help us feel more vibrant during menopause.
How Does Methylene Blue Work?
Think of your cells as tiny engines. Mitochondria are the “powerhouses,” and as we age, they can slow down. Methylene blue acts as a helper, making these engines run more efficiently. This could mean:
Less fatigue
Sharper thinking
Greater resilience against age-related changes
What Does the Research Say?
While big studies are still ongoing, early research shows promise:
Brain support: Methylene blue is being studied for its role in conditions like Alzheimer’s and dementia.
Longevity: It may help reduce inflammation, support DNA repair, and improve cellular energy.
Antioxidant effects: It can help protect cells from damage caused by free radicals.
How Is Methylene Blue Used?
In functional medicine, methylene blue is sometimes used at low doses as a:
Brain booster (nootropic)
Support for chronic fatigue or age-related decline
Tool in longevity and regenerative health programs
Important: Methylene blue is not a supplement to try on your own. It must be prescribed and monitored by a healthcare professional, as the wrong dose can be harmful and it may interact with certain medications (especially antidepressants).
Who Might Benefit?
Women experiencing brain fog or low energy during menopause
Those interested in preventive aging strategies
Anyone looking for new approaches to cognitive or chronic health concerns
The Bottom Line
Methylene blue isn’t a miracle cure, but it’s an exciting area of research in healthy aging. If you’re curious about whether it could be part of your wellness journey, we’re here to help you navigate the options safely.
At Follaine Health, we focus on evidence-based, individualized care for women in perimenopause and menopause. If you’re interested in exploring therapies like methylene blue, we’ll help you do it safely and responsibly—always with your goals and well-being at the center.
Curious about Methylene Blue?
Ready to learn more about how therapies like methylene blue or our personalized menopause programs could support your energy, brain health, and overall well-being?
Book your free 20-minute discovery call with Follaine Health today. Or email us at: info@follainehealth.com
Research References on Methylene Blue
Enhanced Memory and Brain Activity:
Rojas, J.C., et al. (2016). "Methylene Blue Increases Functional MR Imaging Activity in the Human Brain." Radiology, 281(1): 110-118.
This study found that low-dose methylene blue increased activity in brain regions related to memory and attention in healthy adults.
Neuroprotection and Alzheimer’s Disease:
Oz, M., et al. (2011). "Neuroprotective effects of methylene blue in Alzheimer’s disease." Current Alzheimer Research, 8(7): 803-813.
This review discusses methylene blue’s potential to protect brain cells and slow progression in neurodegenerative diseases.
Mitochondrial Support and Cellular Energy:
Atamna, H., et al. (2008). "Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways." Aging Cell, 7(1): 17-26.
This study found that methylene blue can improve mitochondrial function and delay cellular aging in lab models.
Anti-Aging and Skin Health:
Xiao, Y., et al. (2017). "Methylene blue as a promising antioxidant candidate for treating aging-related diseases." Scientific Reports, 7: 2475.
Researchers found that methylene blue protected skin cells from aging and oxidative damage in laboratory studies.









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